WASHINGTON — The federal government will act to ban thousands of flavors used in e-cigarettes, President Donald Trump said Wednesday, responding to a recent surge in underage vaping that has alarmed parents, politicians and health authorities nationwide.

The surprise White House announcement could remake the multibillion-dollar vaping industry, which has been driven by sales of flavored nicotine formulas such as “grape slushie” and “strawberry cotton candy.”

The Food and Drug Administration will develop guidelines to remove from the market all e-cigarette flavors except tobacco, Health and Human Services Secretary Alex Azar told reporters during an Oval Office appearance with the president, first lady Melania Trump and the acting FDA commissioner, Ned Sharpless.

Trump, whose son Barron is 13 years old, said vaping has become such a problem that he wants parents to be aware of what’s happening. “We can’t allow people to get sick and we can’t have our youth be so affected,” he said.

Melania Trump recently tweeted her concerns over the combination of children and vaping, and at the meeting, the president said, “I mean, she’s got a son — together — that is a beautiful, young man, and she feels very, very strongly about it.”

Trump’s first public comments on vaping come as health authorities investigate hundreds of breathing illnesses reported in people who have used e-cigarettes and other vaping devices.

No single device, ingredient or additive has been identified, though many cases involve marijuana vaping.

The restrictions announced by Trump officials would only apply to nicotine vaping products, which are regulated by the FDA.

The FDA has had the authority to ban vaping flavors since 2016, but has previously resisted calls to take that step. Agency officials instead said they were studying if flavors could help smokers quit traditional cigarettes.

But parents, teachers and health advocates have increasingly called for a crackdown on flavors , arguing that they are overwhelmingly to blame for the explosion in underage vaping by U.S. teens, particularly with small, discrete devices such as Juul’s.

“It has taken far too long to stop Juul and other e-cigarettes companies from targeting our nation’s kids with sweet-flavored, nicotine-loaded products,” said Matthew Myers, of the Campaign for Tobacco-Free Kids, in a statement.

Federal law prohibits e-cigarette and all other tobacco sales to those under 18.

But federal health officials said Wednesday that preliminary data shows more than 1 in 4 high school students reported vaping this year, compared with 1 in 5 students in 2018. Federal health officials have called the trend an “epidemic,” and they fear teenagers who vape will eventually start smoking.

More than 80 percent of underage teens who use e-cigarettes say they picked their product because it “comes in flavors that I like,” according to government surveys.

A ban on flavors would be a huge blow to companies like San Francisco-based Juul, which sells mint, fruit and dessert flavored-nicotine pods.

Juul and others have argued that their products are intended to help adult smokers wean themselves off traditional paper-and-tobacco cigarettes.

But a Juul spokesman said in a statement that the company “strongly” agreed with the need for “aggressive action” on flavors.

“We will fully comply with the final FDA policy when effective,” he stated.

The Vapor Technology Association said in a statement the flavor ban would force smokers “to choose between smoking again … or finding what they want and need on the black market.” The group represents vaping manufacturers, retailers and distributors.

Some health experts have seen vaping as offering an “off ramp” for smokers, but the proposed ban casts enormous uncertainty over those hopes.

A 2009 law banned all flavors from traditional cigarettes except menthol. But that law did not apply to e-cigarettes, which were then a tiny segment of the tobacco market.

“We simply have to remove these attractive flavored products from the marketplace until they can secure FDA approval, if they can,” Azar said.