BEIJING (AP) — China expanded its sweeping efforts on Monday to contain a dangerous new virus, extending the Lunar New Year holiday to keep the public at home and avoid spreading infection as the death toll rose to 81.

Mongolia closed its vast border with China, and Hong Kong and Malaysia announced they were barring entry to visitors from the Chinese province at the center of the outbreak following a warning by Chinese officials that the virus’ ability to spread was growing. Travel agencies were ordered to cancel group tours nationwide, adding to the rising economic losses.

Stock markets around the world were down sharply Monday as investors worried the outbreak could hurt the global economy. The Dow Jones Industrial Average fell as much as 550 points following a sell-off in markets in Europe and Japan, and closed with a loss of 453 points, or 1.6%. Airlines, resorts and other companies that rely on travel and tourism suffered steep losses, while apparel and technology companies that get a significant amount of revenue from China also declined.

China has confirmed more than 2,700 cases of the new virus, most in the central city of Wuhan where the illness first surfaced last month. More than 40 cases have been confirmed elsewhere in the world with virtually all of them involving Chinese tourists or people who visited Wuhan recently.

China’s containment efforts began with the Jan. 22 suspension of plane, train and bus links to Wuhan, a city of 11 million people in central China where the virus was first detected last month. That lockdown has expanded to 17 cities with more than 50 million people — the most far-reaching disease-control measures ever imposed.