(AP) — The human and economic toll of the lockdowns against the coronavirus mounted Thursday as India struggled to feed the multitudes, Italy shut down most of its industry, and a record-shattering 3.3 million Americans applied for unemployment benefits in a single week.

As the number of infections worldwide reached a half-million and deaths climbed past 23,000, the damage to people’s livelihoods and their well-being from the effort to flatten the rising curve started to come into focus.

In India, where the country’s 1.3 billion people were under orders to stay home, legions of poor were suddenly thrown out of work, and many families were left struggling for something to eat.

“Our first concern is food, not the virus,” said Suresh Kumar, 60, a bicycle rickshaw rider in New Delhi whose family of six relies on his daily earnings of 300 rupees, or $4. “I don’t know how I will manage.”

India has the world’s second-highest number of people living in extreme poverty. Rickshaw drivers, produce peddlers, maids, day laborers and other low-wage workers form the backbone of the economy, and many live day to day on their pay and have no savings to fall back on.

The Indian government announced a 1.7 trillion rupee ($22 billion) economic stimulus package that will deliver monthly rations of grain and lentils to a staggering 800 million people.

Around the globe, the death toll rose to about 8,200 in Italy, 4,100 in Spain and 1,700 in France, including a 16-year-old.

The U.S. had more than 1,100 deaths, about 400 of them in New York State, the worst hotspot in the nation. Most of those victims were in New York City, where hospitals are getting swamped.

Italy and the United States have essentially tied China, the origin of the outbreak, in confirmed cases, with each country over 80,000 and collectively making up about half the worldwide total.

Louisiana was quickly becoming another smoldering hotspot. The number of new cases there jumped by more than 500 Thursday, for a total of over 2,300, with 86 deaths, including a 17-year-old, the health department said. The higher infection numbers reflected an increase in testing. New Orleans was gearing up for a possible overflow at hospitals, with plans to treat as many as 3,000 patients at the city’s convention center.

From New York’s Fifth Avenue and London’s Piccadilly Circus to the boulevards of Paris and the streets of Rome and Madrid, restaurants, hotels, airlines, giant chains and small shops are all shuttered, and factories across both continents have ground to a halt, as cities, states and entire countries have ordered the closing of nonessential businesses and instructed people to stay home.

Companies in Europe are laying off workers at the fastest pace since 2009, according to surveys of business managers. And the U.S. is bleeding jobs as well: The number of Americans applying for unemployment benefits last week was nearly five times the old record, set in 1982.